Rachel Apa, a 24-year-old from Pennsylvania running her first New York City Marathon, died on Sunday after collapsing at mile 24, two miles from the finish line, and her father says she had a rare muscle condition called rhabdomyolysis.

Her father Steve Apa told US media that Rachel texted "Ow ow" at mile 19 and kept messaging him during the race. Spectators ran to help when she collapsed shortly after 1:30pm, including two doctors who began CPR, the runner's family and race organiser New York Road Runners said.

Medical crews arrived about seven minutes later with a defibrillator, and she was taken by ambulance to Mount Sinai hospital, where she was pronounced dead at around 9:40pm, her father told The New York Times.

The New York City Office of the Chief Medical Examiner told CBS News that no final determination of cause of death has been made, which means the condition named by her family has not yet been officially confirmed.

What rhabdomyolysis is

Rhabdomyolysis, often shortened to "rhabdo", happens when muscle tissue breaks down faster than the body can handle. The damaged muscle releases proteins and electrolytes into the bloodstream, including myoglobin, which can damage the kidneys and, in severe cases, lead to heart rhythm problems and death.

In ordinary life it is most often caused by crush injuries, severe dehydration, heat illness, or extreme and unaccustomed exertion. In endurance sport it is uncommon but not unheard of: marathon runners, ultramarathoners and military recruits in training all produce occasional cases.

The usual treatment is aggressive intravenous fluids and monitoring of kidney function. The key variable is how quickly the condition is recognised — victims often continue exercising because the early symptoms feel like ordinary fatigue and soreness.

Why it is hard to see coming

Rhabdo does not announce itself. Early signs include muscle pain and swelling that seem disproportionate to the effort, dark or cola-coloured urine, and weakness. On a marathon course, those symptoms compete with the ordinary pain of 24 miles, and many runners are encouraged to push through discomfort.

That is the uncomfortable part of this case for race organisers. Endurance events are built on the assumption that participants can judge their own limits, and medical teams are positioned to respond when they cannot. Rachel Apa received CPR within minutes, according to the accounts, which is close to the best-case response time.

Her father told The Times that she had been in "perfect health" and had played Division I field hockey at Bucknell University until 2023, which is the kind of athletic background that makes a sudden death feel inexplicable to a family.

The wider picture

Deaths at major marathons are rare but not zero. Race organisers publish medical protocols, station staff along the course, and in New York deploy a large medical operation that includes doctors and defibrillators. The system is designed to catch cardiac arrests, which are the most common cause of sudden death in endurance events.

Rhabdomyolysis is a different failure mode: it is not a sudden event but a process that builds over hours and can continue after the race. That makes it a harder target for on-course medicine, because the runner may still be moving when the damage is already underway.

What happens next

The medical examiner's determination will establish the official cause, and the family's account may or may not be confirmed by it. Race organisers have not announced changes to their medical protocols, and there is no indication that the event's safety planning is being questioned.

For runners, the case is a reminder that unusual pain, dark urine or confusion during a race are reasons to stop and ask for help rather than to push on. For everyone else, it is a reminder that the most dangerous thing about a marathon is not usually the heart, but the muscle.

Race medicine has improved because organisers now treat the course as a medical environment rather than a sporting one: aid stations with fluids and electrolytes, medical tents at intervals, and staff who can decide to pull a runner out. The gap that remains is between what a runner feels and what a medical team can see. Rhabdomyolysis develops quietly, and by the time the symptoms are unmistakable the kidneys may already be under strain. That is why the advice from sports doctors is consistent: stop early, drink, and get assessed rather than finishing the distance at any cost. Race organisers in New York also publish the location of medical tents and the number to call for help, and the volunteers along the course are trained to flag runners who look unsteady rather than only those who collapse. Those checks are imperfect, but they are the reason race-day deaths are rare rather than routine.

The death lands in the middle of a wider health-policy argument, from the federal transparency rules for health coverage to the White House women's health plan, and it is a reminder of how the FDA classifies product recalls when safety questions arise.